However, significantly positive correlations were detected among the key bacterial taxa (i.e., Parasutterella and Alistipes), UA, IL-1β, IL-6, TNF-α, and MPO, as well as the levels of four metabolic pathways (i.e., lipopolysaccharide biosynthesis, riboflavin metabolism, phenylalanine metabolism, and arginine and proline metabolism) in gout mice (Figure 7A). The gene discussed is MPO; the disease is gout.