However, because the proportion of fibroblasts in nasal polyps is significantly higher than that in the healthy nasal mucosa, in addition to promoting fibrosis, they can also release eochemokine, which plays an important role in stimulating eosinophil recruitment in nasal polyps (156), and also can mediate the release pro-inflammatory IL-6 and IL-8 cytokines (155). The gene discussed is CXCL8; the disease is nasal cavity polyp.