Moreover, several chemokines that are known to play a prominent role in metastasis of cancer cells, namely, CCL2, CCL5, CCL7, CCL20, CXCL1, CXCL3, CXCL5, and CXCL11 were upregulated in CT26 after treatment with CX3CL1 (Figure 5A). This evidence concerns the gene CXCL3 and cancer.