Myelin Oligodendrocyte Glycoprotein (MOG) antibody-associated disease (MOGAD) has recently been described as an entity (1) that encompasses a spectrum of autoimmune demyelinating disorders through the Central Nervous System (CNS), distinct from multiple sclerosis (MS) and neuromyelitis optica spectrum disorders (NMOSD). The gene discussed is MOG; the disease is neuromyelitis optica.