POMC and hereditary pheochromocytoma-paraganglioma: In PSH following TBI, median values of the Adrenocorticotropic Hormone (ACTH) and cortisol concentrations are moderately elevated whereas the neurotransmitter concentrations (noradrenaline, epinephrine, dopamine) are significantly increased to levels that nearly equalize the increase regarded as diagnostic in patients with suspected pheochromocytoma (32).