MUC16 (known as CA125), a well-established antibody, is a useful tool for classification of a variety of tumors, such as adenocarcinomas of the colon, breast carcinomas, malignant mesothelioma, uterine adenomatoid tumor, lung bronchoalveolar carcinoma, ovarian endometrioid and serous carcinomas. Here, MUC16 is linked to colon adenocarcinoma.