(35), through bioinformatics analysis of TCGA data, discovered that miR-146b-5p can bind to the SLFN5 3’UTR and MEG3, demonstrating that MEG3 positively regulates SLFN5 expression and inhibits breast cancer development through sequestration of miR-146b-5p (see Figure 1). This evidence concerns the gene SLFN5 and breast cancer.