In addition, our investigations revealed that YY1 activated STAT3 and FYN signaling in PCa cells without upregulation of β‐catenin (Figure 8J), while depletion of FZD8 in OE‐YY1 LNCaP cells led to inactivation of STAT3 and FYN signaling (Figure 8K). Here, YY1 is linked to posterior cortical atrophy.