LPCAT4 and obesity due to melanocortin 4 receptor deficiency: We determined the protein expression of LysoPhosphatidylCholine Acyl Transferase 4 (LPCAT4) which catalyzes the re-esterification of acyl chains to LPC to regenerate PC with a unique acyl chain combination and observed a reduction of LPCAT4 abundance in female placentas in pregnancy complicated by obesity (Fig. 2C).