CCL2 and obesity due to melanocortin 4 receptor deficiency: In a second reduced model, we eliminated all factors that did not fit the predictive model, in which, in addition to the CXCL10/CCL2 ratio (adjusted OR 15.9, p < 0.001), only the risk factors multiple gestation (adjusted OR 8.4, p = 0.006) and obesity remained (adjusted OR 6.6, p = 0.016) (Fig. 4).