Consistently, the scratch assays also clearly showed that the migration ability of the transfected cells was lower than that of non-transfected CCA cells (Fig. 4A, B, C), and the number of invading cells in the si-ROR1-AS1 group was significantly lower than that of the si-NC group(Fig. 5A, B, C). The gene discussed is ROR1; the disease is cholangiocarcinoma.