These data are consistent with the idea that by 4 weeks post-infection wild type TgVEG parasites are causing significantly less inflammation compared to ΔROCY1 and ΔBFD1 parasites, and that there may be more CD8 + T cells in the brains of mice infected with the mutant parasites to combat was is being sensed as an acute, rather than chronic, infection. Here, CD8A is linked to infection.