Moreover, in the coexpression network analysis of NSUN2 in LIHC, LUAD and HNSC, we showed that NSUN2 indeed participates in the regulation of immunity in cancers, such as LUAD and HNSC, and that NSUN2 participates in the adaptive immune response, interleukin-4 production and other immune-related responses. This evidence concerns the gene IL4 and cancer.