In addition, the levels of some immunostimulators, immunoinhibitors, MHC molecules, chemokines and receptors were positively associated with NSUN2 expression levels in most tumor types, such as LIHC, KIRC and BRCA, while the expression of immune checkpoint-regulated genes was negatively correlated with the expression of NSUN2 in LUSC (Fig 5E). The gene discussed is HLA-C; the disease is neoplasm.