We engineered Ramos Burkitt’s lymphoma cell lines expressing the CT or HLH* EIF3A using the shRNA method as in HEK293T cells and observed a substantial decrease in MYC and MET protein levels in the lymphoma cells expressing the HLH* EIF3A (Table 1, Fig 4A, S6 Fig panel A in S1 File). The gene discussed is MET; the disease is Burkitt lymphoma.