Of all cases examined, 7 (16.67%) specimens of cancer tissues and 0 (0.00%) specimens of paracancerous tissues showed high expression of GPX4, 23 (54.76%) specimens of cancer tissues and 2 (4.76%) specimens of paracancerous tissues demonstrated high expression of NRF2, and 4 (9.52%) specimens of cancer tissues and 1 (2.38%) specimen of paracancerous tissues showed high-expression levels of SLC7A11. The gene discussed is GPX4; the disease is cancer.