The interaction maps uncovered that almost all hub genes were involved in the cancer-associated pathways, comprising RAS/MAPK, epithelial–mesenchymal transition (EMT), TSC/mTOR, receptor tyrosine kinase (RTK) signaling, hormone AR signaling, cell cycle, PI3K/AKT, hormone ER signaling, as well as apoptosis (Figure 9B). This evidence concerns the gene AKT1 and cancer.