Genetic variants in TTN that cause DCM by creating premature truncation of the protein are denoted TTNtv.11 The second most common genetic cause of DCM is rare pathogenic variants in lamin A/C (LMNA), which encodes a ubiquitously expressed nuclear membrane protein that participates in the maintenance of nuclear structure. The gene discussed is LMNA; the disease is familial dilated cardiomyopathy.