This data confirms a well-established role of TTNtv in adult-onset DCM, but not in pediatric-onset DCM.9,10 Rare variants in other established DCM genes including BAG3, DSP, TNNT2, filamin C (FNLC), and MYH7 ranged from 1% to 3% of cases in our cohort. Here, DSP is linked to familial dilated cardiomyopathy.