Interestingly, the results of a recent study also showed that copper bridges the connection between chronic inflammation and tumor development; the authors showed that, in a murine model, the inflammatory response induces copper uptake through the IL-17-STEAP4-XIAP-NFκB axis to promote colon tumorigenesis (Liao et al., 2020). This evidence concerns the gene NFKB1 and neoplasm.