Furthermore, Wu et al. (2020) revealed that circ_0004913 was downregulated in HCC tissues and that the overexpression of circ_0004913 constrained proliferation, EMT and metastasis by acting as a sponge of miR-184 and promoting hepcidin antimicrobial peptide (HAMP) expression. This evidence concerns the gene HAMP and hepatocellular carcinoma.