On analyzing a correlation between the prevalence of raised titers of thyroid autoantibodies in the hypothyroid population under study with the severity of anemia, it was found that 33.9% of hypothyroid patients with raised anti-TPO antibody titers had moderate anemia, while 41.1% of patients with raised anti-TPO antibody titers were having severe anemia (p = 0.036) (Figure 4). This evidence concerns the gene TPO and anemia.