IgM autoantibodies and subsequent C1q deposition could also label S. aureus-phagocytosing, apoptotic neutrophils to increase their apoptotic clearance by macrophages (both IgM- and C1q-deficient mice have increased apoptotic cells and develop SLE-like autoimmune disease (133, 134)). The gene discussed is CD40LG; the disease is systemic lupus erythematosus.