MMP3 and laryngotracheoesophageal cleft: A study including 2014 Caucasian LC patients and 1323 healthy controls showed that MMP-3 -1171 6A/6A was associated with higher risk of LC in never smokers compared with MMP-3 -1171 5A/6A (OR=1.76[95%CI=1.04–2.97]) (134) (Table 4).