Studies in DNA methylation of individuals experiencing domestic violence and sexual assault have identified four genome‐wide differentially methylated genes: BRSK2 and ADCYAP1 in sexual assault,[38] and BDNF and CLPX in domestic violence.[186] Additionally, in vitro PTSD and glucocorticoid response signatures in human induced pluripotent stem cell (hiPSC)‐derived glutamatergic neurons and live cultured peripheral blood mononuclear cells represent exciting new platforms with which to test the genetic and epigenetic mechanisms underlying PTSD.[187]. The gene discussed is ADCYAP1; the disease is post-traumatic stress disorder.