SLC6A4 and post-traumatic stress disorder: For example, in a candidate gene study of PTSD, authors combined all adult traumatic life events and exposure to childhood severity into a single trauma score; they identified significantly increased PTSD risk associated with an interaction between their TRS and the 5‐HTTLPR genotype of the SLC6A4 gene.[104] In two more recent, previously discussed studies: a PTSD GWAS used a constructed TRS from LTE of eight different traumas in the UKBB, including “victim of a violent crime,” “life threatening illness” “witnessing death” and “experiencing sexual assault” (N > 20 000).