NFKB1 and amyotrophic lateral sclerosis: It has been recently observed that some crude extracts and compounds can inhibit the nuclear factor kappa B (NF-kB), which prevents the production of inflammatory cytokines and microglial activation in experimental models of some neurological disorders, such as spinal cord injury, multiple sclerosis and amyotrophic lateral sclerosis (ALS; Kyung et al., 2006; Zhu et al., 2006; Sekiya et al., 2009; Chen et al., 2012; Zhang et al., 2015; Lee et al., 2017; Li et al., 2018; Zhou et al., 2018, 2020; Huang et al., 2019; Salehi et al., 2019; Kim et al., 2020; Sharifi-Rad et al., 2020).