Since a recent report identified SCFAs (propionate and butyrate) role in H3K27ac via p300 (Thomas & Denu, 2021), we conducted a time series experiment in NSCLC cell lines and observed high H3K27ac at 3 h with increase in E‐cadherin at 12 h (Fig 6D). This evidence concerns the gene CDH1 and non-small cell lung carcinoma.