In the current study, propionate showed a standalone EMT marker genes modulation in multiple NSCLC cell lines with an increase in expression of the key epithelial gene, E‐cadherin, along with repression of ZEB1, a master regulator of EMT features including in early tumorigenesis and metastasis in NSCLC (Larsen et al, 2016; Brabletz et al, 2021). Here, ZEB1 is linked to non-small cell lung carcinoma.