CRP and cardiovascular disorder: Significant predictors for severe disease (stages IIB and III) according to clinical-therapeutic staging as proposed by Siddiqi and Mehra included high ferritin, LDH, CRP, a patient age of above 75 years, AEP, and comorbidities, including cardiovascular diseases, lung diseases, diabetes mellitus, and the presence of two or more comorbidities (Table 3).