This resulted in ten NPC prognostic-related genes and six NPC occurrence-related genes, with an intersection of six genes being identified as an EBV-associated occurrence and prognosis gene signature in NPC (C16orf54, CD27, CD53, CRIP1, RARRES3, and TBC1D10C; Figure 9E). Here, CD53 is linked to nasopharyngeal carcinoma.