Compared with the CD8+T cell group, the absolute percentage of trace-labeled tumor cells revealed no significant difference in the M1 + CD8+T cell group and OE-TCF21 + TAM + CD8+T cell group, indicating that the M1 + CD8+T cell group and OE-TCF21 + TAM + CD8+T cell group produced no significant impact on tumor cell killing vs. the CD8+T cell group. The gene discussed is TCF21; the disease is neoplasm.