VEGFA and rheumatoid arthritis: A study demonstrated that EXs produced by MSCs, which overexpress miR-150-5p (Exos-150), can inhibit angiogenesis, migration, and invasion of fibroblast-like synoviocytes, which produce MMPs that degrade type II collagen and relieve the symptoms of RA by downregulating MMP14—which is considered a key enzyme mediating cartilage invasion and vascular endothelial growth factor (VEGF) expression [69].