In rat models of myocardial infarction induced via ligation below the left descending coronary artery, salvianolic acid B combined with ginsenoside Rg1 improves cardiac function through the maximum rates of pressure development for contraction and relaxation, reduces α-SMA expression and MMP-9 activity to reduce myocardial infarct size, prevents or delays the progression of cardiac remodeling, and improves cardiac structure and function [192]. The gene discussed is ACTA1; the disease is myocardial infarction.