JAK2 and thoracic aortic aneurysm: In a study on rat models of 3-aminopropionitrile-induced thoracic aortic aneurysm, salvianolic acid B was found to inhibit the development of aneurysms and improve immune function by inhibiting the Janus kinase 2 (JAK2)/STAT3 signaling pathway, thus reducing malondialdehyde (MDA) and reactive oxygen species (ROS) levels, increasing superoxide dismutase (SOD) levels, and improving oxidative stress in rats.