BDNF and Alzheimer disease: The importance of the present study is major in the field of neurodegenerative diseases since Nosustrophine contains BDNF and corticotropin-releasing factors, among other bioactive agents [15] that reduces the cytotoxic effects of neurodegeneration while promoting an improvement in cognitive function, we aimed to demonstrate that neuropeptides derived from the porcine brain may be protective against neurodegenerative diseases such as AD.