NFKB1 and neoplasm: NF-κB promotes tumor angiogenesis and metastasis by elevating the expressions of vascular endothelial growth factor (VEGF) and matrix metalloproteinase (MMP), increasing cyclin D1 expression for tumor cell proliferation and Bcl-2 for anti-apoptosis and epithelial/mesenchymal transition (EMT) and survival [7].