IFNL2 and infection: At the MOI of 1, control SCGs yielded 2 × 103 ± 4.9 × 102 pfu/mL, whereas IFN-λ2 pre-treated neurons yielded 1.2 × 102 ± 5.1 × 101 pfu/mL virus with a 17-fold mean difference implying that the antiviral effect of type III IFNs in primary neurons is more significant at low MOI infections.