Haugen and coworkers [77] analyzed the leptin status of pre-eclamptic mothers and found that the concentration of leptin in the plasma of pregnant women with preeclampsia was significantly higher than in the plasma of women in physiological pregnancy (34.4 ± 3.2 ng/mL and 22.3 ± 1.1 ng/mL, respectively). Here, LEP is linked to preeclampsia.