Similar to our results, in the NAFLD cell model constructed using HepG2 cells and OA/PA, the key proteins for fatty acid ab initio synthesis, ACC1 and SCD1 [32], and the key proteins for fatty acid ab initio synthesis, FASN [33,34] and SREBP-1 [35] mRNAs, were decreased. Here, SREBF1 is linked to metabolic dysfunction-associated steatotic liver disease.