DHE staining also showed that the CML + PBS group showed the highest red fluorescence to represent approximately 42 ± 2% ROS production, while the CML + rHDL-1 group showed the lowest ROS production (~43% lower (p < 0.001) than the CML + PBS group). This evidence concerns the gene BCR and chronic myelogenous leukemia, BCR-ABL1 positive.