Huaping Mou et al. [80] have suggested that nitidine chloride (54) can inactivate S-phase kinase-associated protein 2 (Skp2) to inhibit ovarian cancer, mainly downregulating Skp2 expression and enhancing the sensitivity of ovarian cancer cells to nitidine chloride, in which p < 0.05. The gene discussed is SKP2; the disease is ovarian cancer.