TNF and injury: Similarly, baicalein, a phenolic flavonoid from the root of Scutellaria baicalensis has been shown to significantly mitigate LPS-induced lung edema and attenuate the levels of IL-1β, TNF-α, IL-6, CINC-3 in broncho alveolar lavage fluid, with marked improvement of lung histopathological symptoms, in an LPS-induced rat model of acute inflammatory lung injury [39].