CD40LG and coinfection: Among these 25 participants with CLD/PTLDS, 44% (11/25) had CDC-positive IgM Lyme immunoblots, and one patient out of 25 (4%) had at least one co-infection; 2 patients (8%) had at least 2 co-infections; and 22 out of 25 patients (88%) had three or more co-infections.