Continue biofilm, microbiome and detoxification/inflammatory support listed above. Continue folic acid, B12 and iron support, as listed above.Depending on laboratory results week 9, adjust glutathione doses and/or folic acid dosing. This will be based on levels of anemia, and methemoglobin levels. L-methyl folate doses can be increased to 5–6 tablets twice a day week 9 if needed for any increases in anemia from higher dose dapsone. Glutathione dosing can increase to 2000 mg TID, if there are any increases in methemoglobin despite methylene blue dosing at 300 mg PO BID. The gene discussed is HBG2; the disease is anemia.