An additional trial, the CRISTAL (Colloids Versus Crystalloids for the Resuscitation of the Critically Ill), was published in 2013 and found no difference in 28-day mortality between a mixed group of colloids (gelatins, dextrans, hydroxyethyl starches, or 4% or 20% of albumin) and crystalloids in patients with hypovolemic and septic shock. Here, ALB is linked to septic shock.