The dysbiosis observed acne skin microbiota can lead to the selection of specific C. acnes lineages, (phylotypes IA1/IA2) and a recent study confirmed that this could lead to production of Christie–Atkins–Munch–Petersen factor (CAMP)1 by C. acnes lineages with strong toll-like receptor (TLR)-2 binding activity to induce inflammation [26,27,28]. Here, TLR2 is linked to acne.