However, besides the presence of the previous genes being alarming, the genes blaCTX (which confers resistance to an extended spectrum of beta-lactamases (ESBLs)) and blaOXA (which confer resistance to carbapenems) potentially impact public health and are considered by the World Health Organization (WHO) as causing increasing concern; the antibiotics these genes confer resistance to are used for difficult-to-treat infections and the increase in bacterial strains resistant to them means a significant reduction in therapeutic alternatives [15,17]. The gene discussed is LACTB; the disease is infection.