Based on the expression of the FDX1, LIPT1, and PDHP genes in the NASH patients, we classified the NASH patients into two clusters: NASH cuproptosis-related clusters (NASH CRCs) A and B. For NASH CRC A, 48 samples were analyzed, and 26 samples were analyzed for NASH CRC B (Figure 4a). The gene discussed is FDX1; the disease is metabolic dysfunction-associated steatohepatitis.