In NASH CRC A and NASH CRC B, FDX1, LIPT1, and PDHP were significantly different, while FDX1, DBT, GCSH, and SLC31A1 were significantly different in HCC CRC A and HCC CRC B (Figure 4d and Figure 5d). Here, FDX1 is linked to metabolic dysfunction-associated steatohepatitis.