Also, Bozek et al. [17] did not find a difference in IFN-γ between PsO (n = 28) and AD (n = 41) in a younger population, whereas children with AD exhibited more than twice as higher serum IL-22 levels compared with children with PsO, presuming that PsO underlies different pathological mechanisms from AD. Here, IL22 is linked to Alzheimer disease.