Suppressive hormonal treatments such as the continuous use of oral contraceptive pills, high-dose progestins, the levonorgestrel-releasing intrauterine device (LNG-IUD), danazol, aromatase inhibitors, selective progesterone receptor modulators, and gonadotropin-releasing hormone agonist (GnRH-a) can temporarily improve symptoms and induce the regression of adenomyosis [6,51]. This evidence concerns the gene CYP19A1 and adenomyosis.