TNF and atherosclerosis: Cheung et al. analyzed the effect of anti-TNF therapy on subclinical atherosclerosis, and six studies measured at least one parameter before and after treatment (24th and 52nd weeks): intima–media thickness, pulse wave velocity, and augmentation index; they found that anti-TNF therapy had no effect on all three parameters at the 24th week and on intima–media thickness at the 52nd week [124].