In another study, 80 patients with various ISUP grades (III–V) were diagnosed with csPCa (SUVmax cutoff ≥ 8 or PI-RADS v2 score ≥ 3) out of 125 high-risk PCa patients [49].68 Ga-PSMA PET/CT achieved a diagnostic accuracy of 92% for csPCa, surpassing the 86.2% of mpMRI. Here, FOLH1 is linked to posterior cortical atrophy.