REN and chronic kidney disease: The mean clinical characteristics of 14 ADPKD patients aged 44 ± 2 years and predominance of female participants (10 out of 14) were moderate CKD (eGFR: 58 ± 8 mL/min/1.73 m2), enlarged kidneys (1.6 ± 0.3 L of TKV), and normal blood pressure (126 ± 3 and 75 ± 2 mmHg for systolic and diastolic blood pressure values, respectively), mostly (10/14 patients) due to renin–angiotensin–aldosterone system (RAAS) antagonism treatment.