CDCA3 and open-angle glaucoma: The results revealed decreased levels of complement component C8 gamma chain (C8G) (FC = 0.83, p = 0.026), complement C6 (FC = 0.81, p = 0.032), and complement factor H (CFH) (FC = 0.77, p = 0.024) in POAG subjects relative to those with cataracts.