IL6 and Anxiety: They found correlations with baseline interleukin-1 receptor antagonist (IL-1ra) (r = −0.393, p = 0.032) and IL-6 (r = −0.407, p = 0.025) with changes in the Brief Psychiatric Rating Scale, Expanded (BPRS-E) manic scores, and insulin-like growth factor binding protein 3 (IGFBP3) (r = −0.446, p = 0.014) with changes in the Brief Psychiatric Rating Scale, Expanded (BPRS-E) anxiety scores.